The 1st International BioDesign Research Conference

The 1st International BioDesign Research Conference

December 1st - 18th, 2020, Virtual

December 1st - 18th, 2020, Online

RegistrationProgram
RegistrationProgram

  Program Overview / Satellite Talk

  Add to calendar IBDRC2020.ics

December 1st

Opening Ceremony and General Session I
Opening ceremony Moderator: AE Shoshana Wodak, VIB-VUB Center for Structural Biology, Belgium

08:00 - 08:20 am

US Pacific Standard Time
Opening by
Marc Tessier-Lavigne, President of Stanford University, USA
Stuart Croft, President of the University of Warwick, UK
Thomas Zacharia, Director of Oak Ridge National Laboratory, USA

Introduction of BioDesign Research, and welcome remarks
08:30 - 09:30 am
Frances H. Arnold, California Institute of Technology, USA

Innovation by evolution: Bringing new chemistry to life (No video)

09:30 - 10:30 am
AB J. Craig Venter, J. Craig Venter Institute, USA
Designing Life (Video Uploaded)


December 2nd-4th

De Novo Design Sessions
Leading organizer: EiC Alfonso Jaramillo, The University of Warwick, UK

December 2   
Session 1: Design and engineering of macromolecules and phages
Chair: AE Mark Isalan, Imperial College London, UK
08:00 - 08:50 am

US Pacific Standard Time
AB David Baker, University of Washington, USA
The coming of age of de novo protein design (Video Uploaded)
08:50 - 09:40 am 
AB David Liu, Harvard University, USA
Base editing and prime editing: Genome editing without double-strand breaks (Video Uploaded)
09:40 - 10:10 am 
AE Mark Isalan, Imperial College London, UK
Engineering the smallest transcription factor: Continuous phage evolution of a 63-amino acid dual activator-repressor (Video Uploaded)
10:10 - 10:40 am 
Tim Lu, Massachusetts Institute of Technology, USA
Using synthetic biology to diagnose and decipher disease (Waiting for permission)
10:40 - 11:10 am
AE Tanja Kortemme, University of California, San Francisco, USA
Sensors and new shapes: Computational design of new molecular geometries and ligand-controlled functions (Waiting for permission)
December 3   
Session 2: Genome design and engineering
Chair: AB AE Rodolphe Barrangou, North Carolina State University, USA
08:00 - 08:50 am

US Pacific Standard Time
AB Jef D. Boeke, NYU Grossman School of Medicine, USA
Tormenting genomes (Waiting for permission)
08:50 - 09:40 am 
AB AE Rodolphe Barrangou, North Carolina State University, USA
Repurposing CRISPR-Cas immune systems to engineer microbiomes and viromes (Video Uploaded)
09:40 - 10:10 am 
Jason Chin, University of Cambridge, UK
Reprogramming the Genetic Code (Waiting for permission)
10:10 - 10:40 am 
Luis Serrano Pubul, Centre for Genomic Regulation (CRG), Spain
Engineering a genome-reduced bacterium for lung therapy (Video Uploaded)
10:40 - 11.10 am
AE Virginia Cornish, Columbia University, USA
Expanding the synthetic capabilities of yeast (Waiting for permission)
December 4   
Session 3: Cell design and engineering
Chair: AE Anke Becker, Philipps University of Marburg, Germany
08:00 - 08:50 am

US Pacific Standard Time
AB George Church, Harvard University, USA
Multiplexing, barcoding & libraries : proteins, viruses & organs (Video Uploaded)
08:50 - 09:40 am
Petra Schwille, Max Planck Institute of Biochemistry, Germany
Re-engineering simplicity from complexity in the quest for minimal cells (Video Uploaded)
09:40 - 10:10 am 
Chris Voigt, Massachusetts Institute of Technology, USA
RiPP discovery & design: New antibiotics and antivirals (Waiting for permission)
10:10 - 10:40 am 
AE Douglas Densmore, Boston University, USA
Hardware, software, wetware co-design applied to synthetic biology (Video Uploaded)
10:40 - 11:10 am 
AE Anke Becker, Philipps University of Marburg, Germany
Engineering synthetic bacterial genome architectures towards exploring organizational principles (Waiting for permission)


December 7th-9th

Microbial Biodesign Sessions
Leading organizer: EiC Alfonso Jaramillo, The University of Warwick, UK

December 7   
Session 1: Cell design and engineering II
Chair: AE Mustafa Khammash, ETH Zurich, Switzerland
08:00 - 08:50 am

US Pacific Standard Time
AB James Collins, Massachusetts Institute of Technology, USA

Harnessing Synthetic Biology to Fight Pathogens (No video)
08:50 - 09:40 am
Terry Hwa, University of California San Diego, USA

Principles of gene regulation quantitatively connect DNA to RNA and proteins in bacteria (No video)
09:40 - 10:10 am
EiC Alfonso Jaramillo, The University of Warwick, UK

Engineering adaptive gene circuits in bacteria mastering game playing by reinforcement learning (Waiting for permission)
10:10 - 10:40 am
AE Mustafa Khammash, ETH Zurich, Switzerland
Designing self-adapting genetic circuits: theory and implementation (Video Uploaded)
10:40 - 11:10 am
AE Nathalie Q. Balaban, The Hebrew University of Jerusalem, Israel
Universal dynamics in bacterial recovery from stress (No video)
December 8   
Session 2: Whole-cell and metabolic biodesign
Chair: AE Ilias Tagkopoulos , University of California Davis, USA
08:00 - 08:50 am

US Pacific Standard Time
AB Richard Lenski, Michigan State University, USA
Dynamics and repeatability of phenotypic and genomic evolution (Video Uploaded)
08:50 - 09:40 am
AB Jay D. Keasling, University of California Berkeley, USA
Engineered polyketide synthases as platform for synthetic chemistry (Waiting for permission)
09:40 - 10:10 am
AE Eriko Takano, University of Manchester, UK

Potentials of synthetic biology for fine and speciality chemical production (Video Uploaded)
10:10 - 10:40 am
AE Ilias Tagkopoulos, University of California Davis, USA
Accelerated knowledge discovery from omics data with active learning (No video)

10:40 - 11:10 am
Markus Covert, Stanford University, USA
Simultaneous cross-evaluation of heterogeneous E. coli datasets via mechanistic simulation (Waiting for permission)
December 9   
Session 3: Protein and RNA circuits biodesign
Chair: AE Beatrix Suess, Technical University, Germany
08:00 - 08:50 am

US Pacific Standard Time
AB Ron Breaker, Yale University, USA
Natural and engineered RNA switches (Video Uploaded)
08:50 - 09:40 am
AE Jeff Hasty, University of California San Diego, USA
Engineered gene circuits: From clocks to tumors and small ecologies (Waiting for permission)
09:40 - 10:10 am
AE Beatrix Suess, Technical University, Germany
Next-level riboswitch development - Implementation of Capture-SELEX allows fast and easy identification of new thetic riboswitches (Video Uploaded)
10:10 - 10:40 am
Erik Winfree, California Institute of Technology, USA
Molecular programming with DNA nanotechnology (Video Uploaded)
10:40 - 11:10 am
AE Yolanda Schaerli, University of Lausanne, Switzerland

Multistable and dynamic CRISPRi-based synthetic circuits (Video Uploaded)


December 10th-14th

Animal and Human Biodesign Sessions
Leading organizer: EiC Stanley Qi, Stanford University, USA

December 10   
Session 1: Design of mammalian systems for diagnostics and therapeutics
Chair: AE Michael Elowitz, California Institute of Technology, USA
08:00 - 08:50 am

US Pacific Standard Time
Michael W. Young, The Rockefeller University, USA

Genes controlling sleep and circadian rhythms (Video Uploaded)
08:50 - 09:40 am
AB Martin Fussenegger, ETH Zurich, Switzerland
Toward a World of ElectroGenetics & The Internet of The Body (No video)
09:40 - 10:10 am
Wendell Lim, University of California San Francisco, USA
Learning to program cellular machines: harnessing cells to treat disease, build tissues, and elucidate design principles (Waiting for permission)
10:10 - 10:40 am
AE Michael Elowitz, California Institute of Technology, USA
Synthetic multicellular circuit design (Waiting for permission)
10:40 - 11:10 am
Rosalyn Moran, King's College London, UK
The active inference and the free energy principle (Video Uploaded)
December 11   
Session 2: Design of mammalian systems for biomedical discovery
Chair: AB AE Pamela Silver, Harvard University, USA
08:00 - 08:50 am

US Pacific Standard Time
AB AE Pamela Silver, Harvard University, USA
Designing diagnostic cells and therapeutic proteins (No video)
08:50 - 09:20 am
AE Ron Weiss, Massachusetts Institute of Technology, USA
Mammalian synthetic biology: from organoids and cancer immunotherapy to precision control (Waiting for permission)
09:20 - 09:50 am
AE Ahmad Khalil, Boston University, USA

Cooperativity and the design of gene regulatory circuits (Waiting for permission)
9:50 - 10:20 am
AE Charles Gersbach, Duke University, USA

Epigenome editing for functional genomics, cell Programming, and gene therapy (Video Uploaded)
10:20 - 10:50 am
Hana El-Samad, University of California San Francisco, USA

Biological feedback loops-- An old problem and a new frontier (Waiting for permission)
December 14   
Session 3: Design of mammalian systems
Chair: AE Matthew Porteus, Stanford University, USA
08:00 - 08:50 am

US Pacific Standard Time
AB Sir Peter J. Ratcliffe, University of Oxford, UK
The implications of switching massively interconnected biological pathways in cancer development; hypoxia signalling as a paradigm (Video Uploaded)
08:50 - 09:20 am
EiC Stanley Qi, Stanford University, USA
Genome design for cell engineering and antivirals (No video)
09:20 - 9:50 am
AE Matthew Porteus, Stanford University, USA
Genome Editing for Complex Engineering of Stem Cells (Video Uploaded)
9:50 - 10:20 am
Yvonne Y. Chen, University of California, Los Angeles, USA

Engineering next-generation T cells for cancer immunotherapy (No video)
10:20 - 10:50 am
Viviana Gradinaru, California Institute of Technology, USA
Engineered gene delivery vectors and microbial opsins for high-precision minimally-invasive study and repair of diseased nervous systems across species (Video Uploaded)


December 15th-16th

Plant Biodesign Sessions
Leading organizer: EiC Xiaohan Yang, Oak Ridge National Laboratory, USA

December 15   
Session 1: New technologies in plant synthetic biology
Chair: AE Bing Yang, University of Missouri, USA
08:00 - 08:50 am

US Pacific Standard Time
AE Jim Haseloff, University of Cambridge, UK
Simple plants as testbeds for bioengineering. (Video Uploaded)
08:50 - 09:40 am
Daniel Voytas, University of Minnesota, USA
Overcoming bottlenecks in editing plant genomes (No video)
09:40 - 10:10 am
Zachary Lippman, Cold Spring Harbor Laboratory, USA

Dissecting and manipulating quantitative trait variation and pleiotropy in plants (No video)
10:10 - 10:40 am
Patrick M Shih, University of California Davis, USA

Redesigning plant metabolism with synthetic biology (No video)
10:40 - 11:10 am
Caixia Gao，Chinese Academy of Sciences, China
Agricultural applications of genome editing in crop plants (No Video)
December 16   
Session 2: Applications of synthetic biology in plants
Chair: AE June Medford, Colorado State University, USA
08:00 - 08:50 am

US Pacific Standard Time
AE June Medford, Colorado State University, USA
Designing a Sustainable Future with Plant Synthetic Biology (No video)
08:50 - 09:40 am
AE Tobias Erb, Max Planck Institute, Germany
Fixing CO2 fixation: From natural to synthetic chloroplasts and back (Video Uploaded)
09:40 - 10:10 am
AE Alistair McCormick, University of Edinburgh, UK

Assembling a liquid-like algal pyrenoid into higher plants (Video Uploaded)
10:10 - 10:40 am
Dario Leister, Ludwig-Maximilians-University Munich, Germany

Redesigning the light reactions of photosynthesis (Video Uploaded)
10:40 - 11:10 am
EiC Xiaohan Yang, Oak Ridge National Laboratory, USA
Challenges and opportunities in the application of biosystems design in plants (Video Uploaded)


December 17th-18th

General Session II and Closing Ceremony

December 17    
General Session II
Chair: AE Shoshana Wodak, VIB-VUB Center for Structural Biology, Belgium
08:00 - 08:50 am

US Pacific Standard Time
Michael Levitt, Stanford University, USA

50 years of force field for Bio-Design: From empirical to knowledge-based, to quantum mechanical to machine learning (Waiting for permission)
08:50 - 09:40 am
Huanming Yang, BGI Group, China
DNA, HGP, & Omics (Video Uploaded)
09:40 - 10:30 am
Ada E. Yonath, Weizmann Institute of Science, Israel

Exploiting architectural principles of tissues and organelles for the design of next generation therapeutics (Video Uploaded)
10:30 - 11:20 am
Leland Hartwell, Arizona State University, USA

Science education: Doing science rather than learning science (Video Uploaded)
December 18    
Closing ceremony: Security and ethics of biosystems design
Chair: AE Gigi Kwik Gronvall, Johns Hopkins University, USA
08:00 - 08:30 am

US Pacific Standard Time
AE Gigi Kwik Gronvall, Johns Hopkins University, USA
Approaching security and ethics for the future bioeconomy (Video Uploaded)
08:30 - 09:00 am
Megan J. Palmer, Stanford University, USA
Engineering Biology from Molecular to Social Scales (Waiting for permission)
09:00 - 09:30 am
AE Diane DiEuliis, National Defense University, USA

Revisiting Biosecurity by Design (Video Uploaded)
09:30 - 10:00 am
Closing remarks by the conveners and Poster award

 Satellite Talk

01
Deepak Balaji T Thimiri Govindaraj
CSIR technology platform for synthetic biology and precision medicine
02
Deepak Balaji T Thimiri Govindaraj
Synthetic biology meets precision medicine: drug repurposing for cancer precision medicine
03
Mohamad Ab, Thermal Control of Engineered T cells
04
Hoe Han Goh, Towards the bioengineering of Nepenthes pitchers for pharming
05
Javier Santos-Moreno, Multistable and dynamic CRISPRi-based synthetic circuits
06
Benjamin Shemer, Immobilized microbial bioreporters enable the detection of buried landmines
07
Nadav Amdursky, Protein-based conductive polymers: From flexible and stretchable electronics to a platform for light-stimuli-responsive material
08
Anis B Baharin, Functional Characterization and Protein Engineering of Prolyl Endoprotease Neprosins from Nepenthes rafflesiana
09
Shanu N Khandelval, Plant Growth Promoting Rhizobacteria (PGPR): Agriculture Evolution
10
Blai Vidiella Rocamora, Synthetic Biology for Terraforming our planet
11
Joana L Rodrigues, Synthetic biology strategies for the production of plant polyphenolic compounds
12
Jose Utrilla, ReProMin: A Quantitative Method for Proteome Reallocation Using Minimal Regulatory Interventions
13
Anjali Mahilkar, Laboratory demonstration of allopatric and mutation-order speciation in Saccharomyces cerevisiae
14
Christopher Dieter Reinkemeier, Designer membraneless organelles equip eukaryotic cells with a second, orthogonal genetic code
15
Ilia Gelfat, Plasmid vectors for in vivo selection‐free use with the probiotic E. coli Nissle
16
Md. Kabir Ahamed, Locally Designed Electroporation Technique for Single Vesicle Manipulation
17
Shai - Zilberzwige-Tal, Genetically Encoding Ultra-Stable Virus-like Particles Encapsulating Functional DNA Nanostructures in Living Bacteria
18
Ayush Pandey, A two-state ribosome and protein model can robustly capture the chemical reaction dynamics of gene expression
19
Hajo Kries, Engineering DNA-templated nonribosomal peptide synthesis
20
Brian c jester, Promoter activity is epigenetically regulated by genome layout, DNA architecture, and positive supercoiling buildup
21
Joaquin Caro Astorga, Bacterial cellulose spheroids as building blocks for 2D and 3D patterned engineered living materials and its regeneration
22
Arezoo Karamivandishi, Improving Cell Engineering in droplet-based microfluidic devices
23
Dan Mark Alon, Engineering a DNAzyme-based Operon System for the Production of DNA Nanoscaffolds in Living Bacteria
24
Phaniendra Alugoju, Using adaptive laboratory evolution of multicellular snowflake clusters in yeast Saccharomyces cerevisiae to study reversibility of evolutionary processes
25
Içvara Aor Barbier, Controlling spatiotemporal pattern formation in a concentration gradient with a synthetic toggle switch
26
Nico Claassens, Towards a sustainable, efficient formate bio-economy: replacing the Calvin cycle by a highly efficient synthetic pathway in a formatotroph
27
Noa Katz, Overcoming the design, build, test (DBT) bottleneck for synthesis of nonrepetitive protein-RNA binding cassettes for RNA applications
28
Ofer Kimchi, Self-assembly based post-translational protein oscillators
29
Ahmad A Mannan, Designing an irreversible metabolic switch for scalable induction of microbial chemical production
30
Juan R Melendez-Alvarez, Emerged Oscillation by Nutrient-Modulating Growth Feedback
31
Freideriki Michailidou, Engineered SAM synthetases for reversible DNA modification in cascade reactions
32
Austin K Stone, Synthetic Antagonistic Competitive Control For Mitigating Unwanted Winner-Take-All Dynamics In Synthetic Gene Circuits
33
Xiaojun Tian, Host Cells: Friend or Foe for Synthetic Gene Circuit Modularity?
34
Cheng Zhu, Rational Design of HIV-1 Immunogens for Carbohydrate-Occluded Neutralization Epitopes
35
Lennart Schada von Borzyskowski, Engineering carbon-neutral photorespiration in Synechococcus elongatus and Arabidopsis thaliana by implementing the beta-hydroxyaspartate cycle

  Quick Link
  Opening Ceremony and General Session I
  De Novo Design Sessions
  Microbial Biodesign Sessions
  Animal and Human Biodesign Sessions
  Plant Biodesign Sessions
  General Session II and Closing Ceremony
  Satellite Talk

Contact us

info@biodesign-conference.com 

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