The 2nd International BioDesign Research Conference

The 2nd International BioDesign Research Conference

December 6th - 17th, 2021, Virtual

December 6th - 17th, 2021, Online

George Church

Harvard University, USA

Multiplexing, barcoding & libraries : proteins, viruses & organs

Abstract

We've helped synthetic and analytic bio-technologies improve exponentially (over ten million-fold) from the dawn of molecular multiplexing and barcoding in 1984, plus synthetic DNA libraries and next-gen sequencing in 2002. Now, these combined with loops of measurements (and occasionally machine learning) produce new enzymes, gene delivery methods, molecular-data-storage and transplantable organs. We have herds of highly edited pigs (up to 42 changes), E.coli with 321 edits making them resistant to most viruses (via genome-wide codon-recoding), and human cells with over 22,000 edits in LINE elements.



Short Bio

George is Professor of Genetics at Harvard Medical School and Professor of Health Sciences and Technology at Harvard and the Massachusetts Institute of Technology (MIT). He is Director of the U.S. Department of Energy Technology Center and Director of the National Institutes of Health Center of Excellence in Genomic Science. He has received numerous awards including the 2011 Bower Award and Prize for Achievement in Science from the Franklin Institute and election to the National Academy of Sciences and Engineering. 

George leads Synthetic Biology at the Wyss Institute, where he oversees the directed evolution of molecules, polymers, and whole genomes to create new tools with applications in regenerative medicine and bio-production of chemicals. 

For details of his research and recent publication, please visit HERE 

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